Electronic aerosol provision system and method

ABSTRACT

A method of control for an aerosol delivery system is disclosed herein. The method generates a first version of an aerosol having at least a first property modified to a first version within a first phase of the inhalation, detects a second phase of the inhalation, and generates a second version of the aerosol having at least the first property modified to a second, different version in response to detection of the second phase of the inhalation.

PRIORITY CLAIM

The present application is a National Phase entry of PCT Application No. PCT/GB2020/052246, filed Sep. 17, 2020, which claims priority from GB Patent Application No. 1914945.9, filed Oct. 16, 2019, which is hereby fully incorporated herein by reference.

FIELD

The present disclosure relates to electronic aerosol provision systems such as nicotine delivery systems (e.g., electronic cigarettes and the like) and a corresponding method of aerosol provision.

BACKGROUND

Electronic aerosol provision systems such as electronic cigarettes (e-cigarettes) generally contain a reservoir of a source liquid containing a formulation, typically including nicotine, from which an aerosol is generated, e.g. through heat vaporization. An aerosol source for an aerosol provision system may thus comprise a heater having a heating element arranged to receive source liquid from the reservoir, for example through wicking or capillary action. Other source materials may be similarly heated to create an aerosol, such as botanical matter, or a gel comprising an active ingredient and/or flavoring. Hence, more generally, the e-cigarette may be thought of as comprising or receiving a payload for heat vaporization.

While a user inhales on the device, electrical power is supplied to the heating element to vaporize the aerosol source (a portion of the payload) in the vicinity of the heating element, to generate an aerosol for inhalation by the user. Such devices are usually provided with one or more air inlet holes located away from a mouthpiece end of the system. When a user sucks on a mouthpiece connected to the mouthpiece end of the system, air is drawn in through the inlet holes and past the aerosol source. There is a flow path connecting between the aerosol source and an opening in the mouthpiece so that air drawn past the aerosol source continues along the flow path to the mouthpiece opening, carrying some of the aerosol from the aerosol source with it. The aerosol-carrying air exits the aerosol provision system through the mouthpiece opening for inhalation by the user.

Usually an electric current is supplied to the heater when a user is drawing or puffing on the device. Typically, the electric current is supplied to the heater, e.g., resistance heating element, in response to either the activation of an airflow sensor along the flow path as the user inhales/draw/puffs or in response to the activation of a button by the user. The heat generated by the heating element is used to vaporize a formulation. The released vapor mixes with air drawn through the device by the puffing consumer and forms an aerosol. Alternatively or in addition, the heating element is used to heat but typically not burn a botanical such as tobacco, to release active ingredients thereof as a vapor or aerosol.

The amount of active ingredient that successfully reaches the user's bloodstream will depend on how well the vaporized or aerosolized payload reaches the user's lungs; meanwhile the flavor experienced by the user will depend on how well the aerosolized payload interacts with the user's mouth. These are potentially contradictory requirements for the payload and/or the providing device.

Various approaches are described herein which seek to help address or mitigate this contradictory requirement.

SUMMARY

In a first aspect, method of control for an aerosol delivery system is provided comprising generating a first version of an aerosol having at least a first property modified to a first version within a first phase of the inhalation; detecting a second phase of the inhalation; and generating a second version of the aerosol having at least the first property modified to a second, different version in response to detection of the second phase of the inhalation.

In another aspect, an aerosol delivery system is provided comprising an aerosol delivery device; a control processor configured to generate a first version of an aerosol having at least a first property modified to a first version within a first phase of the inhalation; a detection processor configured to detect a second phase of the inhalation; and the control processor configured to generate a second version of the aerosol having at least the first property modified to a second, different version in response to detection of the second phase of the inhalation.

Further respective aspects and features of the disclosure are defined in the appended claims.

BRIEF DESCRIPTION OF THE DRAWINGS

Embodiments of the present disclosure will now be described by way of example with reference to the accompanying drawings, in which:

FIG. 1 is a schematic diagram of an aerosol delivery device in accordance with an embodiment of the present disclosure.

FIG. 2 is a schematic diagram of an aerosol delivery device in accordance with an embodiment of the present disclosure.

FIG. 3 is a schematic diagram of an aerosol delivery device in accordance with an embodiment of the present disclosure.

FIG. 4 is a schematic diagram of an aerosol delivery device in accordance with an embodiment of the present disclosure.

FIG. 5 is a schematic diagram of measured airflow in accordance with an embodiment of the present disclosure.

FIG. 6 is a schematic diagram of an aerosol delivery system in accordance with an embodiment of the present disclosure.

FIG. 7 is a flow diagram of a method of control for an aerosol delivery system in accordance with an embodiment of the present disclosure.

DESCRIPTION OF THE EMBODIMENTS

An electronic aerosol provision system and method are disclosed. In the following description, a number of specific details are presented in order to provide a thorough understanding of the embodiments of the present disclosure. It will be apparent, however, to a person skilled in the art that these specific details need not be employed to practice the present disclosure. Conversely, specific details known to the person skilled in the art are omitted for the purposes of clarity where appropriate.

As described above, the present disclosure relates to an aerosol provision system (e.g. a non-combustible aerosol provision system) or electronic vapor provision system (EVPS), such as an e-cigarette. Throughout the following description the term “e-cigarette” is sometimes used but this term may be used interchangeably with (electronic) aerosol or vapor provision system. Similarly, the terms ‘vapor ’ and ‘aerosol’ are referred to equivalently herein.

Generally, the electronic vapor or aerosol provision system may be an electronic cigarette, also known as a vaping device or electronic nicotine delivery system (END), although it is noted that the presence of nicotine in the aerosolizable material is not a requirement. In some embodiments, a non-combustible aerosol provision system is a tobacco heating system, also known as a heat-not-burn system. In some embodiments, the non-combustible aerosol provision system is a hybrid system to generate aerosol using a combination of aerosolizable materials, one or a plurality of which may be heated. Each of the aerosolizable materials may be, for example, in the form of a solid, liquid or gel and may or may not contain nicotine. In some embodiments, the hybrid system comprises a liquid or gel aerosolizable material and a solid aerosolizable material. The solid aerosolizable material may comprise, for example, tobacco or a non-tobacco product. Meanwhile in some embodiments, the non-combustible aerosol provision system generates a vapor or aerosol from one or more such aerosolizable materials.

Typically, the non-combustible aerosol provision system may comprise a non-combustible aerosol provision device and an article for use with the non-combustible aerosol provision system. However, it is envisaged that articles which themselves comprise a means for powering an aerosol generating component may themselves form the non-combustible aerosol provision system. In one embodiment, the non-combustible aerosol provision device may comprise a power source and a controller. The power source may be an electric power source or an exothermic power source. In one embodiment, the exothermic power source comprises a carbon substrate which may be energized so as to distribute power in the form of heat to an aerosolizable material or heat transfer material in proximity to the exothermic power source. In one embodiment, the power source, such as an exothermic power source, is provided in the article so as to form the non-combustible aerosol provision. In one embodiment, the article for use with the non-combustible aerosol provision device may comprise an aerosolizable material.

In some embodiments, the aerosol generating component is a heater capable of interacting with the aerosolizable material so as to release one or more volatiles from the aerosolizable material to form an aerosol. In one embodiment, the aerosol generating component is capable of generating an aerosol from the aerosolizable material without heating. For example, the aerosol generating component may be capable of generating an aerosol from the aerosolizable material without applying heat thereto, for example via one or more of vibrational, mechanical, pressurisation or electrostatic means.

In some embodiments, the aerosolizable material may comprise an active material, an aerosol forming material and optionally one or more functional materials. The active material may comprise nicotine (optionally contained in tobacco or a tobacco derivative) or one or more other non-olfactory physiologically active materials. A non-olfactory physiologically active material is a material which is included in the aerosolizable material in order to achieve a physiological response other than olfactory perception. The aerosol forming material may comprise one or more of glycerine, glycerol, propylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, 1,3-butylene glycol, erythritol, meso-Erythritol, ethyl vanillate, ethyl laurate, a diethyl suberate, triethyl citrate, triacetin, a diacetin mixture, benzyl benzoate, benzyl phenyl acetate, tributyrin, lauryl acetate, lauric acid, myristic acid, and propylene carbonate. The one or more functional materials may comprise one or more of flavors, carriers, pH regulators, stabilizers, or antioxidants.

In some embodiments, the article for use with the non-combustible aerosol provision device may comprise aerosolizable material or an area for receiving aerosolizable material. In one embodiment, the article for use with the non-combustible aerosol provision device may comprise a mouthpiece. The area for receiving aerosolizable material may be a storage area for storing aerosolizable material. For example, the storage area may be a reservoir. In one embodiment, the area for receiving aerosolizable material may be separate from, or combined with, an aerosol generating area.

FIG. 1 is a schematic diagram of an electronic vapor or aerosol provision system such as an e-cigarette 10 in accordance with some embodiments of the disclosure (not to scale). The e-cigarette has a generally cylindrical shape, extending along a longitudinal axis indicated by dashed line LA, and comprises two main components, namely a body 20 and a cartomizer 30. The cartomizer includes an internal chamber containing a reservoir of a payload such as for example a liquid comprising nicotine, a vaporizer (such as a heater), and a mouthpiece 35. References to ‘nicotine’ hereafter will be understood to be merely exemplary and can be substituted with any suitable active ingredient. References to ‘liquid’ as a payload hereafter will be understood to be merely exemplary and can be substituted with any suitable payload such as botanical matter (for example tobacco that is to be heated rather than burned), or a gel comprising an active ingredient or flavoring. The reservoir may be a foam matrix or any other structure for retaining the liquid until such time that it is required to be delivered to the vaporizer. In the case of a liquid or flowing payload, the vaporizer is for vaporizing the liquid, and the cartomizer 30 may further include a wick or similar facility to transport a small amount of liquid from the reservoir to a vaporizing location on or adjacent the vaporizer. In the following, a heater is used as a specific example of a vaporizer. However, it will be appreciated that other forms of vaporizer (for example, those which utilize ultrasonic waves) could also be used and it will also be appreciated that the type of vaporizer used may also depend on the type of payload to be vaporized.

The body 20 includes a re-chargeable cell or battery to provide power to the e-cigarette 10 and a circuit board for generally controlling the e-cigarette. When the heater receives power from the battery, as controlled by the circuit board, the heater vaporizes the liquid and this vapor is then inhaled by a user through the mouthpiece 35. In some specific embodiments the body is further provided with a manual activation device 265, e.g., a button, switch, or touch sensor located on the outside of the body.

The body 20 and cartomizer 30 may be detachable from one another by separating in a direction parallel to the longitudinal axis LA, as shown in FIG. 1 , but are joined together when the device 10 is in use by a connection, indicated schematically in FIG. 1 as 25A and 25B, to provide mechanical and electrical connectivity between the body 20 and the cartomizer 30. The electrical connector 25B on the body 20 that is used to connect to the cartomizer 30 also serves as a socket for connecting a charging device (not shown) when the body 20 is detached from the cartomizer 30. The other end of the charging device may be plugged into a USB socket to re-charge the cell in the body 20 of the e-cigarette 10. In other implementations, a cable may be provided for direct connection between the electrical connector 25B on the body 20 and a USB socket.

The e-cigarette 10 is provided with one or more holes (not shown in FIG. 1 ) for air inlets. These holes connect to an air passage through the e-cigarette 10 to the mouthpiece 35. When a user inhales through the mouthpiece 35, air is drawn into this air passage through the one or more air inlet holes, which are suitably located on the outside of the e-cigarette. When the heater is activated to vaporize the nicotine from the cartridge, the airflow passes through, and combines with, the generated vapor, and this combination of airflow and generated vapor then passes out of the mouthpiece 35 to be inhaled by a user. Except in single-use devices, the cartomizer 30 may be detached from the body 20 and disposed of when the supply of liquid is exhausted (and replaced with another cartomizer if so desired).

It will be appreciated that the e-cigarette 10 shown in FIG. 1 is presented by way of example, and various other implementations can be adopted. For example, in some embodiments, the cartomizer 30 is provided as two separable components, namely a cartridge comprising the liquid reservoir and mouthpiece (which can be replaced when the liquid from the reservoir is exhausted), and a vaporizer comprising a heater (which is generally retained). As another example, the charging facility may connect to an additional or alternative power source, such as a car cigarette lighter.

FIG. 2 is a schematic (simplified) diagram of the body 20 of the e-cigarette 10 of FIG. 1 in accordance with some embodiments of the disclosure. FIG. 2 can generally be regarded as a cross-section in a plane through the longitudinal axis LA of the e-cigarette 10. Note that various components and details of the body, e.g. such as wiring and more complex shaping, have been omitted from FIG. 2 for reasons of clarity.

The body 20 includes a battery or cell 210 for powering the e-cigarette 10 in response to a user activation of the device. Additionally, the body 20 includes a control unit (not shown in FIG. 2 ), for example a chip such as an application specific integrated circuit (ASIC) or microcontroller, for controlling the e-cigarette 10. The microcontroller or ASIC includes a CPU or micro-processor. The operations of the CPU and other electronic components are generally controlled at least in part by software programs running on the CPU (or other component). Such software programs may be stored in non-volatile memory, such as ROM, which can be integrated into the microcontroller itself, or provided as a separate component. The CPU may access the ROM to load and execute individual software programs as and when required. The microcontroller also contains appropriate communications interfaces (and control software) for communicating as appropriate with other devices in the body 10.

The body 20 further includes a cap 225 to seal and protect the far (distal) end of the e-cigarette 10. Typically, there is an air inlet hole provided in or adjacent to the cap 225 to allow air to enter the body 20 when a user inhales on the mouthpiece 35. The control unit or ASIC may be positioned alongside or at one end of the battery 210. In some embodiments, the ASIC is attached to a sensor unit 215 to detect an inhalation on mouthpiece 35 (or alternatively the sensor unit 215 may be provided on the ASIC itself). An air path is provided from the air inlet through the e-cigarette, past the airflow sensor 215 and the heater (in the vaporizer or cartomizer 30), to the mouthpiece 35. Thus, when a user inhales on the mouthpiece of the e-cigarette, the CPU detects such inhalation based on information from the airflow sensor 215.

At the opposite end of the body 20 from the cap 225 is the connector 25B for joining the body 20 to the cartomizer 30. The connector 25B provides mechanical and electrical connectivity between the body 20 and the cartomizer 30. The connector 25B includes a body connector 240, which is metallic (silver-plated in some embodiments) to serve as one terminal for electrical connection (positive or negative) to the cartomizer 30. The connector 25B further includes an electrical contact 250 to provide a second terminal for electrical connection to the cartomizer 30 of opposite polarity to the first terminal, namely body connector 240. The electrical contact 250 is mounted on a coil spring 255. When the body 20 is attached to the cartomizer 30, the connector 25A on the cartomizer 30 pushes against the electrical contact 250 in such a manner as to compress the coil spring in an axial direction, e.g., in a direction parallel to (co-aligned with) the longitudinal axis LA. In view of the resilient nature of the spring 255, this compression biases the spring 255 to expand, which has the effect of pushing the electrical contact 250 firmly against connector 25A of the cartomizer 30, thereby helping to ensure good electrical connectivity between the body 20 and the cartomizer 30. The body connector 240 and the electrical contact 250 are separated by a trestle 260, which is made of a non-conductor (such as plastic) to provide good insulation between the two electrical terminals. The trestle 260 is shaped to assist with the mutual mechanical engagement of connectors 25A and 25B.

As mentioned above, a button 265, which represents a form of manual activation device 265, may be located on the outer housing of the body 20. The button 265 may be implemented using any appropriate mechanism which is operable to be manually activated by the user—for example, as a mechanical button or switch, a capacitive or resistive touch sensor, and so on. It will also be appreciated that the manual activation device 265 may be located on the outer housing of the cartomizer 30, rather than the outer housing of the body 20, in which case, the manual activation device 265 may be attached to the ASIC via the connections 25A, 25B. The button 265 might also be located at the end of the body 20, in place of (or in addition to) cap 225.

FIG. 3 is a schematic diagram of the cartomizer 30 of the e-cigarette 10 of FIG. 1 in accordance with some embodiments of the disclosure. FIG. 3 can generally be regarded as a cross-section in a plane through the longitudinal axis LA of the e-cigarette 10. Note that various components and details of the cartomizer 30, such as wiring and more complex shaping, have been omitted from FIG. 3 for reasons of clarity.

The cartomizer 30 includes an air passage 355 extending along the central (longitudinal) axis of the cartomizer 30 from the mouthpiece 35 to the connector 25A for joining the cartomizer 30 to the body 20. A reservoir of liquid 360 is provided around the air passage 335. This reservoir 360 may be implemented, for example, by providing cotton or foam soaked in liquid. The cartomizer 30 also includes a heater 365 for heating liquid from reservoir 360 to generate vapor to flow through air passage 355 and out through mouthpiece 35 in response to a user inhaling on the e-cigarette 10. The heater 365 is powered through lines 366 and 367, which are in turn connected to opposing polarities (positive and negative, or vice versa) of the battery 210 of the main body 20 via connector 25A (the details of the wiring between the power lines 366 and 367 and connector 25A are omitted from FIG. 3 ).

The connector 25A includes an inner electrode 375, which may be silver-plated or made of some other suitable metal or conducting material. When the cartomizer 30 is connected to the body 20, the inner electrode 375 contacts the electrical contact 250 of the body 20 to provide a first electrical path between the cartomizer 30 and the body 20. In particular, as the connectors 25A and 25B are engaged, the inner electrode 375 pushes against the electrical contact 250 so as to compress the coil spring 255, thereby helping to ensure good electrical contact between the inner electrode 375 and the electrical contact 250.

The inner electrode 375 is surrounded by an insulating ring 372, which may be made of plastic, rubber, silicone, or any other suitable material. The insulating ring is surrounded by the cartomizer connector 370, which may be silver-plated or made of some other suitable metal or conducting material. When the cartomizer 30 is connected to the body 20, the cartomizer connector 370 contacts the body connector 240 of the body 20 to provide a second electrical path between the cartomizer 30 and the body 20. In other words, the inner electrode 375 and the cartomizer connector 370 serve as positive and negative terminals (or vice versa) for supplying power from the battery 210 in the body 20 to the heater 365 in the cartomizer 30 via supply lines 366 and 367 as appropriate.

The cartomizer connector 370 is provided with two lugs or tabs 380A, 380B, which extend in opposite directions away from the longitudinal axis of the e-cigarette 10. These tabs are used to provide a bayonet fitting in conjunction with the body connector 240 for connecting the cartomizer 30 to the body 20. This bayonet fitting provides a secure and robust connection between the cartomizer 30 and the body 20, so that the cartomizer and body are held in a fixed position relative to one another, with minimal wobble or flexing, and the likelihood of any accidental disconnection is very small. At the same time, the bayonet fitting provides simple and rapid connection and disconnection by an insertion followed by a rotation for connection, and a rotation (in the reverse direction) followed by withdrawal for disconnection. It will be appreciated that other embodiments may use a different form of connection between the body 20 and the cartomizer 30, such as a snap fit or a screw connection.

FIG. 4 is a schematic diagram of certain details of the connector 25B at the end of the body 20 in accordance with some embodiments of the disclosure (but omitting for clarity most of the internal structure of the connector as shown in FIG. 2 , such as trestle 260). In particular, FIG. 4 shows the external housing 201 of the body 20, which generally has the form of a cylindrical tube. This external housing 201 may comprise, for example, an inner tube of metal with an outer covering of paper or similar. The external housing 201 may also comprise the manual activation device 265 (not shown in FIG. 4 ) so that the manual activation device 265 is easily accessible to the user.

The body connector 240 extends from this external housing 201 of the body 20. The body connector 240 as shown in FIG. 4 comprises two main portions, a shaft portion 241 in the shape of a hollow cylindrical tube, which is sized to fit just inside the external housing 201 of the body 20, and a lip portion 242 which is directed in a radially outward direction, away from the main longitudinal axis (LA) of the e-cigarette. Surrounding the shaft portion 241 of the body connector 240, where the shaft portion does not overlap with the external housing 201, is a collar or sleeve 290, which is again in a shape of a cylindrical tube. The collar 290 is retained between the lip portion 242 of the body connector 240 and the external housing 201 of the body, which together prevent movement of the collar 290 in an axial direction (e.g., parallel to axis LA). However, collar 290 is free to rotate around the shaft portion 241 (and hence also axis LA).

As mentioned above, the cap 225 is provided with an air inlet hole to allow air to flow when a user inhales on the mouthpiece 35. However, in some embodiments the majority of air that enters the device when a user inhales flows through collar 290 and body connector 240 as indicated by the two arrows in FIG. 4 .

Referring again to FIGS. 1 and 2 , in an embodiment of the present disclosure, an electronic vapor provision system (EVPS) 10 or ‘aerosol delivery device’ such as one of those described previously herein is adapted to provide plural versions of an aerosol.

Accordingly, in embodiments of the present disclosure, the aerosol delivery device comprises a detection processor (such as the control unit mentioned previously, operating under suitable software instructions). Optionally, this detection processor is configured to detect a first phase of an inhalation by a user upon the aerosol delivery device, as will be described in more detail later herein. Alternatively this first phase may be simply assumed, for example upon triggering delivery of vapor by the EVPS (e.g. activation of the EVPS by inhalation).

The aerosol delivery device also comprises a control processor 62 (such as again the control unit mentioned previously, or a separate processor, operating under suitable software instructions) configured to generate a first version of an aerosol having at least a first property modified to a first version, within this first phase of the inhalation. This version of the aerosol may form an initial default output for the EVPS, particularly if the first phase is simply assumed. The first property and the modification will be discussed later herein.

The detection processor is configured to detect a second phase of the inhalation, as described later herein, and the control processor is configured to generate a second version of the aerosol having at least the first property modified to a second, different version in response to detection of the second phase of the inhalation.

In embodiments of the present disclosure, the first property is aerosol particle size, and typically the aerosol particle size of the first version of the aerosol is smaller than the second version of the aerosol. The reason for this arrangement is described later herein.

The aerosol particle size can be changed by in turn changing a property of the aerosol generator. Depending on the type of generator, this may either involve changing a temperature of a heater used to generate the aerosol, or changing a frequency of a vibrator used to generate the aerosol.

For some payloads, increasing the temperature of the heater can increase the rate of vaporization and this results in larger aerosol particle sizes. For other payloads, potentially decreasing the temperature of the heater may cause more rapid droplet formation and coalescence out of pure vapor form, resulting in larger aerosol particle sizes within the EVPS. The approach that is more appropriate for the payload used by the EVPS may therefore be selected, for example at manufacture, automatically (where payloads are interchangeable and detectable) or via a suitable user interface (as described later herein).

Referring now to FIG. 5 , in embodiments of the present disclosure inhalation by the user is detected using an airflow detector 215, or equivalently by a detector for any suitable proxy for airflow such as air speed or dynamic pressure.

Using airflow as the example, but appreciating that airspeed, dynamic pressure or the like could be used instead, then the first phase of the inhalation occurs until the airflow is above a first threshold level (Th1), or the airflow reaches a peak level (Peak).

Hence during an inhalation by the user, the first phase assumes relatively strong or high initial airflow, which will typically (but not necessarily) reach an empirically determined threshold level indicative of this strong initial phase. Meanwhile, whether this threshold is met (or detected for), the airflow from the inhalation will, at some point, peak; this may be an instantaneous peak or a smoothed peak (as a non-limiting example, averaged over a rolling window of 0.1 or 0.2 seconds).

Meanwhile the second phase of the inhalation occurs after airflow drops below a second threshold level (Th2), or the airflow reaches a peak level (Peak). Again, if used, then the peak may be instantaneous or smoothed, as above.

It will be appreciated that optionally the first phase can be assumed until the second phase is detected, and as such optionally the completion of the first phase need not be separately detected at all. Clearly, where the first and second phases are delineated by the same event (e.g. peak inhalation) then the transition is clear and in effect instantaneous. Meanwhile if the first phase is deemed to be complete once the first threshold is reached (but before a peak is reached, or before the airflow falls below the second threshold, as appropriate), then the EVPS may either continue in the first phase, or use this intervening time to transition towards or into the second phase (e.g., by moving to a neutral or transitional heater temperature, or vibration frequency). Various possible intervening times are represented in FIG. 5 by horizontal arrowed lines.

The effect of these embodiments is that a first version of the aerosol with typically smaller aerosol particles is produced during a first detected or assumed inhalation phase, and then in response to detection of the second inhalation phase a second version of the aerosol with typically larger aerosol particles is produced.

The reason behind this is that the inventors have appreciated that during the course of an inhalation on the EVPS (or similar devices), the air inhaled during the initial part of the inhalation may have relatively higher velocity particles and will tend to reach the lungs during an inhalation whilst the air inhaled during the latter part of the inhalation may have relatively lower velocity particles and will tend to reach the mouth. As a result, different versions of aerosols adapted for delivery to the lungs or to the mouth can be delivered during different phases of the inhalation to increase the effectiveness of the delivery (for example including or increasing the proportion of nicotine in the first phase, and including or increasing the proportion of flavoring in the second phase, or excluding or reducing the proportion of flavor in the first phase, and excluding or reducing the proportion of nicotine in the second phase). Similarly, smaller particles will tend to reach the lungs (and particularly the deep lungs where the air pathways narrow) whilst larger particles will tend to reach the mouth.

Therefore, providing smaller particles during the higher velocity first phase of inhalation will improve delivery of vapor to the lungs, and hence delivery of an active ingredient into the bloodstream, whilst providing larger particles during the lower velocity second phase of inhalation will improve delivery of vapor to the mouth, and hence delivery of flavor.

The result is that a similar amount of active ingredient and flavor can be delivered to the user by a smaller amount of vapor, because it is delivered more efficiently than if the aerosol particles are not differentiated in response to the inhalation profile of the user.

In other words, embodiments of the present disclosure differentiate the generated aerosol during different phases of inhalation, targeting the lungs during the initial high velocity part of the inhalation, and targeting the mouth during the lower velocity end part of the inhalation. As described above, this can be done by controlling the heater temperature to create smaller and then larger particle sizes (or equally by control of a vibration atomizer), but potentially also or instead by switching between payloads during the inhalation (for example with a nicotine payload first, then a flavor payload second) by having two wicks, heaters or the like.

Hence in embodiments of the present disclosure, different payloads may be used for the first and second inhalation phases to exploit the existing tendency toward delivery to the lungs in the first phase, and delivery to the mouth in the second phase, and may optionally also be differentiated by particle size to increase this tendency further, as explained previously herein.

Hence in embodiments of the present disclosure, the first property is the payload that is being aerosolized and hence the constituents of the aerosol. It will be appreciated that when this is in addition to differentiating aerosol size, this would be a second property or a parallel first property, but otherwise may be considered the same.

Accordingly, in an embodiment of the disclosure, the EVPS comprises two aerosol generators each in connection to a respective one of two payload sources, and the control processor is configured to generate the first and second versions of the aerosol by selectively activating each of the aerosol generators to generate a respective aerosol comprising a respective payload (e.g., different constituents or ratios of constituents, for example changing the presence or level of nicotine and flavoring).

It will be appreciated that such activations can overlap to create a mix, and the control processor is then configured to effectively change the balance of the mix in response to detection of the second phase, and optionally in response to detection of completion of the first phase (for example by transitioning to a more even mix in a transitional period between phases, where one occurs).

It will be appreciated that the two aerosol generators may not necessarily use the same generation mechanism, but that where at least a first aerosol generator is a heater it is in thermal connection with at least a portion of the respective payload, and where at least a first aerosol generator is a vibrator it is in mechanical connection with at least a portion of the respective payload.

It will be appreciated that improving uptake of an active ingredient during a first, higher velocity and deep-lung phase of inhalation, by using smaller aerosol particle sizes or targeted selection of active payload, and improving sensation of flavor during a second lower velocity and shallower phase of inhalation, by using larger aerosol particle sizes or targeted selection of flavor payload, could be improved further by more accurately predicting at least the start of the second phase for the particular user; this is because there is likely to be a delay, either in temperature change or in vaporization of a payload, during transition to the second phase; therefore by predicting when the second phase (and optionally the first phase) occur, this delay can potentially be accounted for or mitigated.

Hence in embodiments of the present disclosure, the control processor is configured to measure airflow during a plurality of inhalations of the user, and the control processor is configured to model one or more inhalation airflow profiles of the user based upon these measurements.

The or each profile is indicative of the typical behavior of the user of the EVPS during inhalation.

An inhalation airflow profile describes the velocity or amount of air inhaled through the electronic cigarette of the EVPS over the course of a puff by the user.

An inhalation airflow profile may optionally be defined parametrically, to varying degrees of approximation. A profile may thus define a target shape of an inhalation as a time history or curve, or may define the peak airflow (or a similar measure of intensity) and the duration for the inhalation profile, or may define the integral of the airflow and the time, in either case optionally together with one or more further parameters responsive to the inhalation curve (such as a timing for a peak within the inhalation).

Such profiles may thus characterize a short, low-dosage puff, or a long, higher dosage puff, or any other type or style of inhalation by the user. Similarly, the profiles may vary depending on whether the user's inhalation is shallow or deep. Hence, the profile may be of arbitrary length, depending on the corresponding inhalation behavior, and the airflow parameter described by the profile may vary over that time as the characteristics of the user's inhalation varies.

Optionally a profile may be predefined at manufacture or by a distributor, or may be loaded later by a user (as described later herein). Profile data may be stored in a local data storage such as RAM or flash memory.

The inhalation performed by a user may thus be compared to the profile description, whether this is by tracing an inhalation with respect to a time history or curve, or comparing the difference between a target profile position on an inhalation intensity or time plot and the user's current position, either after an inhalation is complete, or as it progresses.

Accordingly, the control processor is configured to compare airflow measurements to the one or more modelled inhalation airflow profiles, and if the measurement matches a modelled inhalation airflow profile to within a predetermined tolerance, then the control processor is configured to predict one or more of the start of the second phase of inhalation, and the end of the first phase of inhalation, based on that modelled inhalation airflow profile. Equivalently, instead of matching to a predetermined tolerance, the closest existing model could be selected. Optionally this could itself be subject to matching to a predetermined tolerance, outside which either a default behavior is used or an additional model is initiated using the current measurements, thereby adapting to different styles of the user.

Referring again to FIG. 5 , this time as an example inhalation profile, it will be appreciated that the integral under the graph represents the amount of air inhaled, and hence over time is indicative of cumulative inhalation and hence the speed and depth of inhalation. Consequently any of the timing at which Th1 is met, or the level of the peak or the timing of the peak, or the integral itself, or initial the gradient of the airflow, or the timing at which Th2 is met may be used to characterize a profile and select a closest modelled profile or (in a training mode) to select or create a profile to update with this new data.

Referring to FIG. 6 , it will be appreciated that the system as described herein may be a self-contained system in which an aerosol delivery device such as an e-cigarette comprises the detection and control processors and any required data storage, but optionally the system may comprise two components, such as an aerosol delivery device 10 and a mobile phone or similar device (such as a tablet) 100 operable to communicate with the e-cigarette, for example via a Bluetooth® scheme.

The mobile phone may then comprise one or more of the profile storage or selection or training means (e.g. suitable RAM, flash memory and processor), the detection processor, and the control processor, with input measurement data and output commands as appropriate being communicated by the Bluetooth® scheme between the e-cigarette and mobile phone.

As suggested previously above, inhalation profiles may also be downloaded, or optionally created or curated, using a suitable interface on the mobile phone.

Hence, in embodiments of the present disclosure, an aerosol delivery system comprises a mobile communications device operable to wirelessly communicate with the aerosol delivery device, the mobile communications device comprising one or more of the detection processor and the control processor. In this case, it will be appreciated that the detection processor or control processor may be provided by a CPU of the mobile device operating under suitable software instruction. It will also be appreciated that the role of either the detection processor or the control processor may be shared between multiple CPUs, either in the phone, in the EVPS or distributed between the two.

Referring now to FIG. 7 , a method of control for an aerosol delivery system comprises:

Optionally detecting a first phase of an inhalation by a user upon the aerosol delivery device, or simply assuming the first phase upon activation of the EVPS to deliver vapor;

In a first step s710, generating a first version of an aerosol having at least a first property modified to a first version within the first phase of the inhalation;

In a second step s720, detecting a second phase of the inhalation; and

In a third step s730, generating a second version of the aerosol having at least the first property modified to a second, different version in response to detection of the second phase of the inhalation.

It will be apparent to a person skilled in the art that variations in the above method corresponding to operation of the various embodiments of the apparatus as described and claimed herein are considered within the scope of the present disclosure, including but not limited to:

-   -   the first property being aerosol particle size;         -   the aerosol particle size of the first version being smaller             than the second version;         -   generating the first and second versions of the aerosol by             changing a property of an aerosol generator to change the             resulting aerosol particle size, the property of the aerosol             generator being one selected from the list consisting of a             temperature of a heater used to generate the aerosol, a             frequency of a vibrator used to generate the aerosol, and a             source of the aerosol (e.g., different aerosol paths, modes             of generation, base materials etc).     -   the first property being the payload being aerosolized.         -   the payload of the first version comprising an ingredient             whose active effect occurs when absorbed into the             bloodstream, and the payload of the second version             comprising an ingredient whose active effect occurs when             tasted;         -   the aerosol delivery device comprising two aerosol             generators each in connection to a respective one of two             payload sources, and the method comprising the step of             generating the first and second versions of the aerosol by             selectively activating each of the aerosol generators to             generate a respective aerosol comprising a respective             payload;             -   at least a first aerosol generator being a heater, and                 in thermal connection with at least a portion of the                 respective payload;             -   at least a first aerosol generator being a vibrator, and                 in mechanical connection with at least a portion of the                 respective payload;     -   inhalation being detected using an airflow detector;         -   the first phase of the inhalation occurring until the             airflow is above a first threshold level;         -   the first phase of the inhalation occurring until the             airflow reaches a peak level;         -   the second phase of the inhalation occurring after the             airflow drops below a second threshold level;         -   the second phase of the inhalation occurring after the             airflow reaches a peak level;     -   measuring airflow during a plurality of inhalations of the user,         and modelling one or more inhalation airflow profiles of the         user based upon these measurements; and     -   measuring airflow during an inhalation of the user, comparing         the measurement to the one or more modelled inhalation airflow         profiles, and if the measurement matches a modelled inhalation         airflow profiles to within a predetermined tolerance, predicting         one or more selected from the list consisting of the end of the         first phase of inhalation and the start of the second phase of         inhalation.

It will be appreciated that the above methods may be carried out on conventional hardware suitably adapted as applicable by software instruction or by the inclusion or substitution of dedicated hardware, such as for example e-cigarette or similar, or an e-cigarette operating in combination with a mobile phone or similar.

Thus, the required adaptation to existing parts of a conventional equivalent device may be implemented in the form of a computer program product comprising processor implementable instructions stored on a non-transitory machine-readable medium such as a floppy disk, optical disk, hard disk, PROM, RAM, flash memory or any combination of these or other storage media, or realized in hardware as an ASIC (application specific integrated circuit) or an FPGA (field programmable gate array) or other configurable circuit suitable to use in adapting the conventional equivalent device. Separately, such a computer program may be transmitted via data signals on a network such as an Ethernet, a wireless network, the Internet, or any combination of these or other networks.

The various embodiments described herein are presented only to assist in understanding and teaching the claimed features. These embodiments are provided as a representative sample of embodiments only, and are not exhaustive or exclusive. It is to be understood that advantages, embodiments, examples, functions, features, structures, or other aspects described herein are not to be considered limitations on the scope of the disclosure as defined by the claims or limitations on equivalents to the claims, and that other embodiments may be utilized and modifications may be made without departing from the scope of the claimed disclosure. Various embodiments of the disclosure may suitably comprise, consist of, or consist essentially of, appropriate combinations of the disclosed elements, components, features, parts, steps, means, etc., other than those specifically described herein. In addition, this disclosure may include other subject matter not presently claimed, but which may be claimed in future. 

1. A method of control for an aerosol delivery system, comprising: generating a first version of an aerosol having at least a first property modified to a first version within a first phase of an inhalation; detecting a second phase of the inhalation; and generating a second version of the aerosol having at least the first property modified to a second version, wherein the second version differs from the first version, in response to detection of the second phase of the inhalation.
 2. The method of claim 1, wherein the first property is the constituents of a payload being aerosolized.
 3. The method of claim 2, wherein a first in which the payload of the first version comprises first ingredient whose active effect occurs when absorbed into the bloodstream, and a second payload of the second version comprises a second ingredient whose active effect occurs when tasted.
 4. The method of claim 2, in which the aerosol delivery device comprises two aerosol generators each in connection to a respective one of two payload sources; and the method further comprises the step of: generating the first and second versions of the aerosol by selectively activating each of the aerosol generators to generate a respective aerosol comprising a respective payload.
 5. The method of claim 4, wherein at least a first aerosol generator is a heater, and is in thermal connection with at least a portion of the respective payload.
 6. The method of claim 4, wherein at least a first aerosol generator is a vibrator, and is in mechanical connection with at least a portion of the respective payload.
 7. The method of claim 1, wherein the first property is aerosol particle size.
 8. The method of claim 7, wherein the aerosol particle size of the first version is smaller than the aerosol particle size of the second version.
 9. The method of claim 7, wherein generating the first and second versions of the aerosol comprises changing a property of an aerosol generator to change the resulting aerosol particle size, the property of the aerosol generator being one selected from a list consisting of: i. a temperature of a heater used to generate the aerosol; ii. a frequency of a vibrator used to generate the aerosol; and iii. a source of the aerosol.
 10. The method of claim 1, wherein inhalation is detected as an airflow using an airflow detector.
 11. The method of claim 10, wherein the first phase of the inhalation occurs until the airflow is above a first threshold level.
 12. The method of claim 10, wherein the first phase of the inhalation occurs until the airflow reaches a peak level.
 13. The method of claim 10, wherein the second phase of the inhalation occurs after the airflow drops below a second threshold level.
 14. The method of claim 10, wherein the second phase of the inhalation occurs after the airflow reaches a peak level.
 15. The method of claim 1, further comprising: measuring airflow during a plurality of inhalations of the user; and modelling one or more inhalation airflow profiles of the user based upon these measurements.
 16. The method claim 15, further comprising: measuring airflow during a next inhalation of the user; comparing the measurement to the one or more modelled inhalation airflow profiles; and in response to a the measurement matching a modelled inhalation airflow profiles to within a predetermined tolerance, predicting one or more selected from a list consisting of: i. the end of the first phase of inhalation; and ii. the start of the second phase of inhalation.
 17. An aerosol delivery system, comprising: an aerosol delivery device; a control processor configured to generate a first version of an aerosol having at least a first property modified to a first version within a first phase of an inhalation; a detection processor configured to detect a second phase of the inhalation; and the control processor configured to generate a second version of the aerosol having at least the first property modified to a second version, wherein the second version is different from the first version, in response to detection of the second phase of the inhalation.
 18. The aerosol delivery system of claim 17, wherein the first property is constituents of a payload being aerosolized.
 19. The aerosol delivery system of claim 18, wherein the aerosol delivery device comprises two aerosol generators each in connection to a respective one of two payload sources; and the control processor is configured to generate the first and second versions of the aerosol by selectively activating each of the aerosol generators to generate a respective aerosol comprising a respective payload.
 20. The aerosol delivery system of claim 17, wherein the first property is aerosol particle size.
 21. The aerosol delivery system of claim 20, wherein the aerosol particle size of the first version is smaller than the aerosol particle size of the second version.
 22. The aerosol delivery system of claim 20, wherein the control processor is configured to generate the first and second versions of the aerosol by changing a property of an aerosol generator to change the resulting aerosol particle size, the property of the aerosol generator being one selected from a list consisting of: i. a temperature of a heater used to generate the aerosol; ii. a frequency of a vibrator used to generate the aerosol; and iii. a source of the aerosol.
 23. The aerosol delivery system of claim 17, wherein inhalation is detected as an airflow using an airflow detector.
 24. The aerosol delivery system of claim 23, wherein the first phase of the inhalation occurs until one or more from a list consisting of: i. the airflow being above a first threshold level; and ii. the airflow reaching a peak level.
 25. The aerosol delivery system of claim 23, wherein the second phase of the inhalation occurs after one or more from a list consisting of: i. the airflow dropping below a second threshold level; and ii. the airflow reaching a peak level.
 26. The aerosol delivery system of claim 17, wherein: the control processor is configured to measure airflow during a plurality of inhalations of the user; and the control processor is configured to model one or more inhalation airflow profiles of the user based upon these measurements.
 27. The aerosol delivery system of claim 26, wherein the control processor is configured to compare airflow measurements to the one or more modelled inhalation airflow profiles; and in response to a measurement matching a modelled inhalation airflow profiles to within a predetermined tolerance, the control processor is configured to predict one or more selected from a list consisting of: i. the end of the first phase of inhalation; and ii. the start of the second phase of inhalation.
 28. The aerosol delivery system of claim 17, further comprising: a mobile communications device operable to wirelessly communicate with the aerosol delivery device; and wherein the mobile communications device comprises one or more from a list consisting of: i. the detection processor; and ii. the control processor.
 29. The aerosol delivery system of claim 17, further comprising: at least a first payload for aerosolization by the aerosol delivery device. 